1. Nas - "Ether"
This crushes me as a diehard Jay-Z fan, but come on. "Ether" is a blistering response to "Takeover." Nas takes aim at Jay-Z's street credibility, personal life, and career, igniting a fierce battle between the two rap heavyweights. The track is often regarded as a turning point in their feud, with many considering Nas the victor, especially with Jay's eventual response not hitting the heights it needed to. "Ether" is now a verb because of this song, so it's extended itself into the world for people who don't even get the reference. That's power.
Most savage lyric:
"How much of Biggie's rhymes is gonna come out your fat lips"- Nas / Ether